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Abstract #2127

Investigating the effect of hyperoxia and hypercapnia on T2* and S0 calculated from multi-echo BOLD data at 7T.

Alex A Bhogal 1 , Jeroen C.W. Siero 2 , Marielle E. Philippens 2 , Esben T. Petersen 2 , Martijn Froeling 2 , Jeroen Hendrikse 2 , Manus J. Donahue 3 , and Hans Hoogduin 2

1 University Medical Center, Utrecht, Utrecht, Netherlands, 2 University Medical Center, Utrecht, Netherlands, 3 Vanderbilt University School of Medicine, Tennessee, United States

Hypercapnia and hyperoxia, induced using targeted gas challenges, may be used to probe physiological effects related to the Blood Oxygen Level Dependent (BOLD) signal. Multi-echo BOLD data is acquired allowing changes in T2* and S0 parameters in response to breathing challenges to be examined. Results are explained in the context of physiological phenomenon.

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