Abstract #2172
Plaque characteristics, burden and distribution assessment with high-resolution intracranial vessel wall imaging at 3 tesla MRI
Nikki Dieleman 1 , Wenjie Yang 2 , Jill Abrigo 3 , Ka Lok Lee 3 , Chiu Wing Chu 3 , Anja G. van der Kolk 1 , Jeroen C.W. Siero 1 , Ka Sing Wong 2 , Jeroen Hendrikse 1 , and Xiang Yan Chen 2
1
Department of Radiology, University Medical
Center Utrecht, Utrecht, Utrecht, Netherlands,
2
Department
of Medicine, Chinese University of Hong Kong, Shatin,
Hong Kong, China,
3
Department
of Imaging and Interventional Radiology, Chinese
University of Hong Kong, Shatin, Hong Kong, China
In this study we qualitatively evaluated intracranial
plaque characteristics (contrast enhancement, thickening
and configuration), total plaque burden and distribution
in patients with an MCA stenosis using a 3D T1-weighted
volumetric isotropic turbo spin-echo acquisition (VISTA)
vessel wall sequence at 3 tesla. The sequence was able
to identify basic intracranial plaque characteristics
and assess total plaque burden and distribution. We
demonstrate that intracranial atherosclerotic plaques
are mainly associated with an eccentric configuration
and a focal thickening pattern. Most of the lesions were
found in the anterior circulation, corresponding to
similar distributions found for ischemic strokes.
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