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Abstract #2172

Plaque characteristics, burden and distribution assessment with high-resolution intracranial vessel wall imaging at 3 tesla MRI

Nikki Dieleman 1 , Wenjie Yang 2 , Jill Abrigo 3 , Ka Lok Lee 3 , Chiu Wing Chu 3 , Anja G. van der Kolk 1 , Jeroen C.W. Siero 1 , Ka Sing Wong 2 , Jeroen Hendrikse 1 , and Xiang Yan Chen 2

1 Department of Radiology, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Department of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong, China, 3 Department of Imaging and Interventional Radiology, Chinese University of Hong Kong, Shatin, Hong Kong, China

In this study we qualitatively evaluated intracranial plaque characteristics (contrast enhancement, thickening and configuration), total plaque burden and distribution in patients with an MCA stenosis using a 3D T1-weighted volumetric isotropic turbo spin-echo acquisition (VISTA) vessel wall sequence at 3 tesla. The sequence was able to identify basic intracranial plaque characteristics and assess total plaque burden and distribution. We demonstrate that intracranial atherosclerotic plaques are mainly associated with an eccentric configuration and a focal thickening pattern. Most of the lesions were found in the anterior circulation, corresponding to similar distributions found for ischemic strokes.

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