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Abstract #2179

Quantitative Evaluation of Collateral Perfusion Using Multi-delay 3D pCASL in Patients with Middle Cerebral Artery Stenosis

Xin Lou 1 , Ning Ma 2 , Jinghao Lyv 1 , Yang Xu 1 , Zhenyu Zhou 3 , Bing Wu 3 , and Lin Ma 1

1 Department of Radiology, Chinese PLA General Hospital, Beijing, China, 2 Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Beijing, China, 3 MR Research Center, GE Healthcare, Beijing, China

DSA remains the method that can best evaluate collateral extents, but it is relatively time-consuming, invasive, costly, and cannot provide quantitative measurement. Determining the presence and adequacy of collateral blood flow is important in patients with severe intracranial stenosis or occlusion due to collateral flow can maintain cerebral circulation and may be another potential therapeutic target in acute ischemic stroke. Our study suggests that multi-post labeling delay time 3D pCASL technique may be a useful tool to quantitative the collateral perfusion in patients with intracranial arterial stenosis.

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