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Abstract #2180

Monitoring pH and energy metabolim in subacute stroke using 31 P and 1 H MRSI

Ulrich Pilatus 1 , Johann-Philipp Zllner 2 , Elke Hattingen 1 , and Oliver Singer 2

1 Neuroradiology, Goethe-University Frankfurt, Frankfurt, Germany, 2 Neurology, Goethe-University Frankfurt, Germany

31P and 1H Magnetic resonance spectroscopic imaging (MRSI) was used to measure pH and energy metabolism in subacute stroke (mean of 6 days after stroke). We found two inorganic phosphate signals in stroke tissue, which indicates a fraction at alcalotic pH (7.38) and one at regular pH (7.03). High energy metabolites were decreased but not totally depleted.

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