Abstract #2239
Volumetric MRSI as a tool to guide and monitor radiotherapy treatment in patients with glioma
Anouk Marsman 1 , Sulaiman Sheriff 2 , Doris D. Lin 1 , Andrew A. Maudsley 2 , Lawrence Kleinberg 3 , and Peter B. Barker 1
1
Russell H. Morgan Department of Radiology
and Radiological Science, Johns Hopkins University
School of Medicine, Baltimore, Maryland, United States,
2
Department
of Radiology, University of Miami Miller School of
Medicine, Miami, Florida, United States,
3
Department
of Radiation Oncology & Molecular Radiation Sciences,
Johns Hopkins University School of Medicine, Baltimore,
Maryland, United States
Volumetric echo-planar spectroscopic imaging (EPSI) is a
promising technique for mapping human brain tumors,
based on elevated lesion choline (Cho) signals. This
abstract reports the results of an interim analysis of
an on-going project to determine if post-surgical EPSI
has a role in radiotherapy planning in subjects with
high-grade glioma, as well as to investigate the effects
of treatment on tumor metabolism.
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