Abstract #2278
Diagnostic Performance of Dynamic Susceptibility Contrast Perfusion in Glioma Grading: Comparison of Cerebral Blood Volume among Different Analysis Software
Kohsuke Kudo 1 , Ikuko Uwano 2 , Toshinori Hirai 3 , Hideo Nakamura 4 , Noriyuki Fujima 1 , Fumio Yamashita 2 , Jonathan Goodwin 2 , Satomi Higuchi 2 , and Makoto Sasaki 2
1
Diagnostic and Interventional Radiology,
Hokkaido University Hospital, Sapporo, Hokkaido, Japan,
2
Ultra-High
Field MRI, Iwate Medical University, Morioka, Japan,
3
Radiology,
Kumamoto University, Kumamoto, Japan,
4
Neurosurgery,
Kumamoto University, Kumamoto, Japan
The purpose of the present study was to compare rCBV
value of DSC perfusion and diagnostic performance of
rCBV for discriminating low grade and high grade tumor
among different software packages in patients with
cerebral glioma. CBV maps were generated by 11 different
algorithms of four commercially available software and
one academic program. Diagnostic performances of rCBV
for glioma grading were not statistically significant
among post-processing software. However, rCBV values and
cut off values for discriminating low grade and high
grade gliomas were different among algorithms.
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