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Abstract #2295

T1 weighted imaging in middle ear cholesteatoma

Koji Yamashita 1 , Akio Hiwatashi 1 , Osamu Togao 1 , Kazufumi Kikuchi 1 , Tomoyuki Okuaki 2 , Nozomu Matsumoto 3 , Koji Kobayashi 4 , and Hiroshi Honda 1

1 Clinical Radiology, Graduate School of Medical Science, Kyushu University, Fukuoka, Fukuoka, Japan, 2 Philips Electronics Japan, Tokyo, Japan, 3 Otorhinolaryngology, Kyushu University, Fukuoka, Japan, 4 Medical Technology, Kyushu University hospital, Fukuoka, Japan

T1 weighted imaging is sensitive to slow spin motions in tissue, and may provide information about the macromolecular properties of tissues. Therefore clinical application of the technique is of increasing importance. The aim of our study was to investigate the feasibility of T1 imaging in diagnosing cholesteatoma. In this study, we compared the differences of average T1 values between cholesteatoma and non-cholesteatoma group. As a result, cholesteatoma can be distinguished from other middle ear diseases. Although the precise mechanism of pathogenesis is not fully elucidate, our results will help us for a better understanding of biological behavior in cholesteatoma.

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