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Abstract #2336

Robust Inter-Pulse Phase Correction for Brain Perfusion Imaging at Very High Field using Pseudo-Continuous Arterial Spin Labeling (pCASL)

Lydiane Hirschler 1,2 , Clment Stphan Debacker 1,2 , Jrme Voiron 2 , Jan Warnking 1,3 , and Emmanuel Luc Barbier 1,3

1 Universit Grenoble Alpes, Grenoble Institut des Neurosciences, Grenoble, France, 2 Bruker Biospin, Ettlingen, Germany, 3 Inserm, U836, Grenoble, France

Performing pseudo-continuous arterial spin labeling (pCASL) at very high magnetic field is challenging as B0 inhomogeneities at the labeling plane, away from the isocenter, strongly affect the spins phase and thus inversion efficiency. This study shows that, for an unbalanced pCASL, performing a label and a control phase increment correction improves perfusion signal, corrects asymmetry between brain hemispheres arising when labeling far from isocenter at high field, and preserves high image quality at the same time.

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