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Abstract #2353

Application of Multi-TI arterial spin-labeling MRI in brain tumors: Comparison with dynamic susceptibility contrast

Shuang Yang 1 , Tianyi Qian 2 , Jianwei Xiang 3 , Yingchao Liu 4 , Peng Zhao 4 , Josef Pfeuffer 5 , Guangbin Wang 1 , and Bin Zhao 1

1 Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, China, 2 MR Collaborations NE Asia, Siemens Healthcare, Beijing, China, 3 Shandong Medical Imaging Research Institute, Taishan Medical University, Jinan, Shandong, China, 4 Neurosurgery, Shandong provincial Hospital Affiliated to Shandong University, Shandong, China, 5 Application Development, Siemens Healthcare, Erlangen, Germany

A 3D multi-TI arterial spin-labeling (mTI-ASL) protocol had been applied to measure the blood perfusion of patients with brain tumor. This study present the feasibility of mTI-ASL for brain tumors in the clinical environment and compare it with dynamic-susceptibility contrast-enhanced perfusion imaging (DSC) to test the hypothesis whether mTI-ASL could substitute DSC in brain tumor cases. The results shows the performances of mTI-ASL in measuring CBF and timing information of blood flow were consistent with DSC. Thus, the perfusion information and the results obtained by dynamic contrast-enhanced technique could be obtained with only one single contrast agent injection.

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