Abstract #2353
Application of Multi-TI arterial spin-labeling MRI in brain tumors: Comparison with dynamic susceptibility contrast
Shuang Yang 1 , Tianyi Qian 2 , Jianwei Xiang 3 , Yingchao Liu 4 , Peng Zhao 4 , Josef Pfeuffer 5 , Guangbin Wang 1 , and Bin Zhao 1
1
Shandong Medical Imaging Research Institute,
Shandong University, Jinan, Shandong, China,
2
MR
Collaborations NE Asia, Siemens Healthcare, Beijing,
China,
3
Shandong
Medical Imaging Research Institute, Taishan Medical
University, Jinan, Shandong, China,
4
Neurosurgery,
Shandong provincial Hospital Affiliated to Shandong
University, Shandong, China,
5
Application
Development, Siemens Healthcare, Erlangen, Germany
A 3D multi-TI arterial spin-labeling (mTI-ASL) protocol
had been applied to measure the blood perfusion of
patients with brain tumor. This study present the
feasibility of mTI-ASL for brain tumors in the clinical
environment and compare it with dynamic-susceptibility
contrast-enhanced perfusion imaging (DSC) to test the
hypothesis whether mTI-ASL could substitute DSC in brain
tumor cases. The results shows the performances of
mTI-ASL in measuring CBF and timing information of blood
flow were consistent with DSC. Thus, the perfusion
information and the results obtained by dynamic
contrast-enhanced technique could be obtained with only
one single contrast agent injection.
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