Quantifying Cerebral Blood Flow: A Comparison of Two Non-invasive Perfusion Imaging Techniques
Gena Matta 1,2 , Andrew D Robertson 1 , Sandra E Black 1,3 , and Bradley J MacIntosh 1,3
Canadian Partnership for Stroke Recovery,
Sunnybrook Research Institute, Toronto, Ontario, Canada,
of Waterloo, Waterloo, Ontario, Canada,
of Toronto, Toronto, Ontario, Canada
Arterial-spin labelling (ASL) and phase-contrast
angiography (PCA) provide two non-invasive methods to
quantify the total cerebral blood flow. The primary aim
of this study was to assess the agreement of CBF
two cerebrovascular cohorts: overt stroke and small
vessel diseases (SVD), and to (2) assess the
repeatability of each technique within a stroke cohort.
We observed significant differences between the total
CBF estimates produced by each modality, therefore we
state that caution is warranted when comparing total CBF
between modalities among patients with cerebrovascular
disease. Intra-subject repeatability was high, however,
for both approaches.
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