Abstract #2584
Comparison of High Resolution LGE and High Resolution Electro-Anatomical Mapping for Imaging of the Ventricular Arrhythmia Substrate in a Swine Model of Ventricular Tachycardia
Sbastien Roujol 1 , Tamer A. Basha 1 , Cory Tschabrunn 1 , Kraig V. Kissinger 1 , Warren J. Manning 1,2 , Mark E. Josephson 1 , Elad Anter 1 , and Reza Nezafat 1
1
Department of Medicine, Beth Israel
Deaconess Medical Center and Harvard Medical School,
Boston, Massachusetts, United States,
2
Department
of Radiology, Beth Israel Deaconess Medical Center and
Harvard Medical School, Boston, Massachusetts, United
States
ICD therapy is the first line therapy for the prevention
of sudden cardiac death. Reduced incidence of ICD
therapy can be achieved when combined with catheter
based ventricular tachycardia (VT) ablation in patient
with history of myocardial infarction. However, the
recurrence rate of VT/VF after VT ablation is about ~50%
in these patients and better technique for VT substrate
identification are needed. Late gadolinium enhancement
(LGE) CMR has the potential for non-invasive assessment
of the VT substrate, which consists of reentry circuits
near or within a chronic scar. In this study, we sought
to utilize a high-resolution 3D LGE sequence with 1 mm3
isotropic spatial resolution to image a surrogate of the
VT substrate in swine model of VT.
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