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Abstract #2591

In-vivo free-breathing DTI & IVIM of the whole human heart using a real-time slice-followed SE-EPI navigator-based sequence: a reproducibility study in healthy volunteers.

Kvin Moulin 1,2 , Pierre Croisille 1,3 , Thorsten Feiweier 4 , Benedicte M.A. Delattre 1 , Hongjiang Wei 1 , Benjamin Robert 2 , Olivier Beuf 1 , and Magalie Viallon 1,3

1 CREATIS; CNRS (UMR 5220); INSERM (U1044); INSA Lyon; Universit de Lyon, Lyon, France, 2 Siemens Healthcare France, Saint-Denis, France, 3 Department of Radiology, Centre Hospitalier Universitaire de Saint- Etienne, Universit Jean-Monnet, France, 4 Healthcare, Siemens AG, Erlangen, Germany

In-vivo cardiac diffusion using either the Intra-Voxel Incoherent Motion (IVIM) model or the Diffusion Tensor Imaging (DTI) model shows promise to provide new insights into heart pathologies. However, due to the combined challenge of respiratory and heart motion, currently proposed acquisition methods are quite demanding for unhealthy patients. In this study, we propose to use the motion information provided by a navigator to prospectively update in real time the position of the diffusion-weighted slices in order to offer an efficient free-breathing strategy for rapid and improved cardiac diffusion acquisition using a single-shot Spin-Echo EPI sequence (SE-EPI).

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