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Abstract #2599

High Spatial Resolution Myocardial T 2 * Mapping at 7.0 T Reveals Differences between Healthy Volunteers and Patients with Hypertrophic Cardiomyopathy

Till Huelnhagen 1 , Fabian Hezel 1 , Andreas Pohlmann 1 , Andreas Graessl 1 , Jan Rieger 2 , Darius Lysiak 2 , Christof Thalhammer 1 , Peter Kellman 3 , Marcel Prothmann 4 , Jeanette Schulz-Menger 4,5 , and Thoralf Niendorf 1,5

1 Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine (MDC), Berlin, Germany, 2 MRI.TOOLS GmbH, Berlin, Germany, 3 National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, 4 Dept. of Cardiology and Nephrology, HELIOS Klinikum Berlin-Buch, Berlin, Germany, 5 Experimental and Clinical Research Center, a joint cooperation between the Charite Medical Faculty and the Max-Delbrueck Center, Berlin, Germany

This work examines the capability of T 2 * mapping at 7.0 T to differentiate between normal myocardium and myocardial tissue affected by hypertrophic cardiomyopathy. This is the first patient study report on cardiac MR at 7.0 T. Results show, that high spatial resolution myocardial T 2 * mapping at 7.0 T reveals differences between healthy volunteers and patients with hypertrophic cardiomyopathy. This observation holds the promise to provide means for an MR based biomarker for the risk stratification of HCM.

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