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Abstract #2608

First and Second Order Motion Compensated Spin-Echo Diffusion Tensor Imaging of the Human Heart

Christian Torben Stoeck 1,2 , Constantin von Deuster 1,2 , Martin Genet 1 , David Atkinson 3 , and Sebastian Kozerke 1,2

1 Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2 Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, 3 Centre for Medical Imaging, University College London, London, United Kingdom

Spin-echo based diffusion weighted sequences allow for single-shot acquisitions but are highly sensitive to cardiac motion. In this work second order motion compensated diffusion encoding was implemented and compared to first order motion compensation during systolic contraction of the heart. Second order motion compensation was found to yield an extended systolic window suitable for imaging when compared to first order motion compensation (210 vs. 90 ms) thereby enabling spin-echo DTI at various points during the cardiac cycle.

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