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Abstract #2623

Myocardium and blood T 1 measurement using SMART 1 Map in healthy volunteers at 1.5T

Pauline Ferry 1,2 , Glenn S. Slavin 3 , Anne Menini 4 , Anja Brau 5 , Damien Mandry 1,6 , Laurent Bonnemains 1,6 , Jacques Felblinger 1,7 , and Marine Beaumont 7,8

1 IADI, Universit de Lorraine, Nancy, France, 2 U947, INSERM, Nancy, France, 3 GE Healthcare, Bethesda, MD, United States, 4 GE Global Research, Munich, Germany, 5 GE Healthcare, Munich, Germany, 6 University Hospital, Nancy, France, 7 CIC-IT 1433, INSERM, Nancy, France, 8 CIC-IT, University Hospital, Nancy, France

T1 is an intrinsic tissue parameter. Moreover, myocardial extracellular volume, a surrogate for fibrosis extent estimation, can be derived from pre- and post-injection T1 measurements. This parameter is altered in most, if not all, cardiomyopathies, making it of paramount interest SMART1Map is a single-point method that has been proposed for a true myocardium T1 measurement. This method also provides insensitivity to heart rhythm variation since it adapts the longitudinal magnetization saturation recovery curve sampling to each subject. In this study, we applied SMART1map on healthy volunteers in order to assess the average normal true myocardium T1 value.

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