Abstract #2623
Myocardium and blood T 1 measurement using SMART 1 Map in healthy volunteers at 1.5T
Pauline Ferry 1,2 , Glenn S. Slavin 3 , Anne Menini 4 , Anja Brau 5 , Damien Mandry 1,6 , Laurent Bonnemains 1,6 , Jacques Felblinger 1,7 , and Marine Beaumont 7,8
1
IADI, Universit de Lorraine, Nancy, France,
2
U947,
INSERM, Nancy, France,
3
GE
Healthcare, Bethesda, MD, United States,
4
GE
Global Research, Munich, Germany,
5
GE
Healthcare, Munich, Germany,
6
University
Hospital, Nancy, France,
7
CIC-IT
1433, INSERM, Nancy, France,
8
CIC-IT,
University Hospital, Nancy, France
T1 is an intrinsic tissue parameter. Moreover,
myocardial extracellular volume, a surrogate for
fibrosis extent estimation, can be derived from pre- and
post-injection T1 measurements. This parameter is
altered in most, if not all, cardiomyopathies, making it
of paramount interest SMART1Map is a single-point method
that has been proposed for a true myocardium T1
measurement. This method also provides insensitivity to
heart rhythm variation since it adapts the longitudinal
magnetization saturation recovery curve sampling to each
subject. In this study, we applied SMART1map on healthy
volunteers in order to assess the average normal true
myocardium T1 value.
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