Abstract #2625
Free-Breathing Multi-Slice Myocardial T1 Mapping Using Inversion Recovery Slice Interleaved Spoiled Gradient Echo Imaging
Sbastien Roujol 1 , Jihye Jang 1,2 , Tamer A. Basha 1 , Sebastian Weingrtner 1,3 , Sophie Berg 1 , and Reza Nezafat 1
1
Department of Medicine, Beth Israel
Deaconess Medical Center and Harvard Medical School,
Boston, Massachusetts, United States,
2
Computer
Aided Medical Procedures, Technische Universitt
Mnchen, Munich, Germany,
3
Computer
Assisted Clinical Medicine, University Medical Center
Mannheim, Heidelberg University, Mannheim, Germany
Native myocardial T1 mapping sequences usually employed
a balanced steady state free precession readout, which
is susceptible to the B0 field inhomogeneity, T2
dependent and sensitive to magnetization transfer. These
effects lead to regional T1 variations and potential
reduced accuracy. Gradient recalled echo (GRE) imaging
has been proposed for post-contrast T1 mapping but its
feasibility for native myocardial T1 mapping remain to
be investigated further. In this study, we sought to
develop and evaluate a multi-slice T1 mapping sequence
using GRE readout and characterize its accuracy,
precision, and reproducibility for in-vivo native
myocardial T1 mapping.
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