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Abstract #2625

Free-Breathing Multi-Slice Myocardial T1 Mapping Using Inversion Recovery Slice Interleaved Spoiled Gradient Echo Imaging

Sbastien Roujol 1 , Jihye Jang 1,2 , Tamer A. Basha 1 , Sebastian Weingrtner 1,3 , Sophie Berg 1 , and Reza Nezafat 1

1 Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States, 2 Computer Aided Medical Procedures, Technische Universitt Mnchen, Munich, Germany, 3 Computer Assisted Clinical Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany

Native myocardial T1 mapping sequences usually employed a balanced steady state free precession readout, which is susceptible to the B0 field inhomogeneity, T2 dependent and sensitive to magnetization transfer. These effects lead to regional T1 variations and potential reduced accuracy. Gradient recalled echo (GRE) imaging has been proposed for post-contrast T1 mapping but its feasibility for native myocardial T1 mapping remain to be investigated further. In this study, we sought to develop and evaluate a multi-slice T1 mapping sequence using GRE readout and characterize its accuracy, precision, and reproducibility for in-vivo native myocardial T1 mapping.

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