Meeting Banner
Abstract #2636

Can quantitative texture analysis on cardiac magnetic resonance differentiate hypertrophic cardiomyopathy patients at high risk of sudden cardiac death and candidates for implantable cardioverter-defibrillator placement from those at low risk?

Rebecca E Thornhill 1,2 , Julie Robillard 3,4 , Michael Gollob 5 , Carole Dennie 1,2 , Alexander Dick 6,7 , Edith Kolozsi 6 , and Elena Pena 1,2

1 Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada, 2 Radiology, University of Ottawa, Ottawa, ON, Canada, 3 Radiology, Montreal Heart Institute, Montreal, PQ, Canada, 4 Radiologie, Universit de Montral, Montreal, PQ, Canada, 5 Electrophysiology, Peter Munk Cardiac Centre, Toronto, ON, Canada, 6 Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada, 7 Medicine, University of Ottawa, Ottawa, ON, Canada

Evidence of late gadolinium enhancement (LGE) has been associated with the development of arrhythmias and sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). One of the challenges is how to improve the predictive value of LGE in HCM as enhancement may appear heterogeneous. Texture analysis was applied to quantify enhancement heterogeneity in HCM patients considered at high risk of SCD and those who are not. These features were significantly elevated in patients considered at high risk of SCD, even in non-hypertrophic, non-fibrotic segments (ie, normal appearing). Quantitative textural features show potential for assisting in risk stratification in HCM.

This abstract and the presentation materials are available to members only; a login is required.

Join Here