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Abstract #2638

Eliminating the Impact of Myocardial Lipid Content on Myocardial T1 Mapping Using a Spectrally-Selective Inversion Pulse

Maryam Nezafat 1,2 , Sbastien Roujol 2 , Jihye Jang 2 , Tamer Basha 2 , and Ren M. Botnar 1

1 Kings College London, London, UK, United Kingdom, 2 Beth Israel Deacons Medical Center and Harvard Medical School, Boston, MA, United States

Quantitative T1 mapping provides myocardial tissue characterization for assessment of interstitial diffuse fibrosis in cardiomyopathies. Various T1 mapping methods with different acquisition scheme have been proposed to sample the magnetization recovery curve. Presence of fatty infiltration is common in many patients with cardiomyopathies. However, current T1 measurements are influenced by lipid contents in the myocardium. The aim of our study is to develop a T1 mapping sequence which eliminates the impact of fat presence on T1 measurements.

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