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Abstract #2654

3D Large Coverage Atherosclerotic Plaque Assessment with Single Scan (APASS): Preliminary Application in Carotid Artery and Femoral Artery

Shuo Chen 1 , Zechen Zhou 1 , Huijun Chen 1 , Bida Zhang 2 , Rui Li 1 , Jinnan Wang 3,4 , Chun Yuan 1,3 , and Xihai Zhao 1

1 Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, Beijing, China, 2 Healthcare Department, Philips Research China, Shanghai, China, 3 Department of radiology, University of Washington, Seattle, United States, 4 Philips Research North America, Briarcliff Manor, NY, United States

Atherosclerosis is a systemic disease that affects different vascular beds simultaneously. Previously developed techniques are limited by the small coverage, low slice resolution, and long scan time in large coverage atherosclerosis imaging. In this study, we sought to develop a 3D large coverage Atherosclerotic Plaque Assessment with Single Scan (APASS) technique that can be used to image the plaque burden and compositions simultaneously in one scan in a short time at different vascular beds. APASS was validated on healthy volunteers for both carotid artery imaging (160mm, < 4min) and femoral artery imaging (250 mm, <8min).

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