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Abstract #2657

Carotid Pulse Wave Velocity Measurements Using Accelerated High Temporal Resolution MRI

Abdallah G. Motaal 1,2 , Wouter WV Potters 1 , Huiming Dong 2 , Luc M. J. Florack 3 , Klaas Nicolay 2 , Aart J Nederveen 1 , Gustav J Strijkers 2,4 , and Bram F Coolen 1

1 Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 2 Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 3 Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, North Brabant, Netherlands, 4 Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands

A common method to assess vessel wall stiffness is measuring the velocity of the pulse wave (PWV) created by cardiac contraction. PWV can be determined by measuring the time delay between the flow curves at two different slice locations. These measurements require sufficient spatial resolution for accurate flow quantification, as well as high temporal resolution with respect to the travel time of the pulse wave between the two slices. Here, we present a new MRI method for carotid PWV assessment, where we combine retrospective triggering and compressed sensing reconstruction, resulting in flow measurements with in-plane spatial resolution of 0.85 mm and temporal resolution of 200 frames/cardiac cycle.

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