Abstract #2657
Carotid Pulse Wave Velocity Measurements Using Accelerated High Temporal Resolution MRI
Abdallah G. Motaal 1,2 , Wouter WV Potters 1 , Huiming Dong 2 , Luc M. J. Florack 3 , Klaas Nicolay 2 , Aart J Nederveen 1 , Gustav J Strijkers 2,4 , and Bram F Coolen 1
1
Department of Radiology, Academic Medical
Center, Amsterdam, Netherlands,
2
Department
of Biomedical Engineering, Eindhoven University of
Technology, Eindhoven, Netherlands,
3
Mathematics
and Computer Science, Eindhoven University of
Technology, Eindhoven, North Brabant, Netherlands,
4
Department
of Biomedical Engineering and Physics, Academic Medical
Center, Amsterdam, Netherlands
A common method to assess vessel wall stiffness is
measuring the velocity of the pulse wave (PWV) created
by cardiac contraction. PWV can be determined by
measuring the time delay between the flow curves at two
different slice locations. These measurements require
sufficient spatial resolution for accurate flow
quantification, as well as high temporal resolution with
respect to the travel time of the pulse wave between the
two slices. Here, we present a new MRI method for
carotid PWV assessment, where we combine retrospective
triggering and compressed sensing reconstruction,
resulting in flow measurements with in-plane spatial
resolution of 0.85 mm and temporal resolution of 200
frames/cardiac cycle.
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