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Abstract #2660

Feasibility and Signal Analysis of DANTE-TSE with Variable Flip Angles for Intracranial Vessel Wall Imaging at 7 Tesla

Olivia Viessmann 1 , Linqing Li 1 , and Peter Jezzard 1

1 Nuffield Department of Clinical Neurosciences, Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, United Kingdom

DANTE is a low flip angle preparation module for black-blood and CSF suppression. In combination with a TSE with variable flip angle (SPACE) it is suitable for intracranial vessel wall imaging. Low flip angle methods are particularly important at 7 Tesla where SAR limits the application of sequences using large flip angles for blood and CSF nulling. We implemented DANTE-SPACE at 7 Tesla and analysed the signal loss due to brain movement, the effect of B1 inhomogeneity and relaxation time variations on the signal level. A clinically relevant protocol for intracranial vessel wall imaging is presented.

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