Abstract #2673
Thin-slice Acquisition using Saturation Spin Labeling (TASSL) MRA
Robert R. Edelman 1,2 , Shivraman Giri 3 , Ian Murphy 2 , and Ioannis Koktzoglou 1,4
1
Radiology, NorthShore University
HealthSystem, Evanston, Illinois, United States,
2
Radiology,
Feinberg School of Medicine, Northwestern University,
Chicago, Illinois, United States,
3
Siemens
Healthcare, Chicago, Illinois, United States,
4
Radiology,
Pritzker School of Medicine, University of Chicago,
Chicago, Illinois, United States
Inversion-based arterial spin labeling (ASL) techniques
have been used for two decades to create nonenhanced MRA
of the cerebrovascular circulation and other vascular
systems. Potential limitations of inversion-based ASL
MRA include signal loss within distal vessels due to T1
relaxation during transit of the labeled spins, and
reduced scan efficiency due to the requirement for a
long inflow time (typically ≈1 sec). We propose a new
saturation-based approach for ASL MRA called TASSL that
improves scan efficiency and reduces sensitivity to
arterial transit time. The technique was tested in the
circle of Willis and peripheral arterial system.
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