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Abstract #2673

Thin-slice Acquisition using Saturation Spin Labeling (TASSL) MRA

Robert R. Edelman 1,2 , Shivraman Giri 3 , Ian Murphy 2 , and Ioannis Koktzoglou 1,4

1 Radiology, NorthShore University HealthSystem, Evanston, Illinois, United States, 2 Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States, 3 Siemens Healthcare, Chicago, Illinois, United States, 4 Radiology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois, United States

Inversion-based arterial spin labeling (ASL) techniques have been used for two decades to create nonenhanced MRA of the cerebrovascular circulation and other vascular systems. Potential limitations of inversion-based ASL MRA include signal loss within distal vessels due to T1 relaxation during transit of the labeled spins, and reduced scan efficiency due to the requirement for a long inflow time (typically ≈1 sec). We propose a new saturation-based approach for ASL MRA called TASSL that improves scan efficiency and reduces sensitivity to arterial transit time. The technique was tested in the circle of Willis and peripheral arterial system.

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