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Abstract #2734

Ventilator Gated 4D Flow MRI in Pediatric Patients with CHD: Initial Feasibility and Internal Validation

Patrick Magrath 1,2 , Stanislas Rapacchi 2 , Fei Han 1,2 , Peng Hu 2 , J. Paul Finn 2 , and Daniel B. Ennis 1,2

1 Bioengineering, University of California, Los Angeles, California, United States, 2 Radiology, University of California, Los Angeles, California, United States

The purpose of this study was an initial evaluation of a 4D-flow workflow consisting of: 1) a ventilator-gated 4D-flow acquisition that leverages the regularity of respiratory motion provided in these cases; and 2) 4D flow segementation using a recently developed co-registered, high resolution, ventilator gated, CE-MRA technique made possible through the use of an intravascular contrast agent (Ferumoxytol). These initial results demonstrate that a workflow consisting of ventilator gated 4D flow acquisition coupled with segmentation using the MUSIC MRA sequence made possible by an intravascular contrast agent is feasible and provides a straightforward workflow.

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