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Abstract #2750

The effect of resolution on viscous dissipation measured with 4D-flow MRI in patients with Fontan circulation: Evaluation using computational fluid dynamics

Merih Cibis 1 , Kelly Jarvis 2,3 , Michael Markl 2,3 , Michael Rose 2,4 , Cynthia Rigsby 2,4 , Alex J Barker 2 , and Jolanda J Wentzel 1

1 Biomedical Engineering, Erasmus MC, Rotterdam, Netherlands, 2 Radiology, Northwestern University, Chicago, Illinois, United States, 3 Biomedical Engineering, Northwestern University, Chicago, Illinois, United States, 4 Medical Imaging, Ann& Robert H Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States

Viscous dissipation inside Fontan circuit might be associated with the exercise performance of Fontan patients. Information on viscous dissipation might therefore be used in clinical assessment of these patient and can be calculated in-vivo by using flow MRI data. However the magnitude of viscous dissipation might depend on the spatial resolution of the MRI data. We investigated the influence of resolution on the estimated viscous dissipation. By using computational fluid dynamics (CFD) simulations, we showed that decreased spatial resolution results in underestimated viscous dissipation. However we were able to capture the differences in viscous dissipation between patients also at lower spatial resolution.

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