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Abstract #2778

Can we make QSI clinically feasible? : A study of short step QSI

Koji Sakai 1 , Jun Tazoe 2 , Hajime Yokota 2 , Thorsten Feiweier 3 , Kentaro Akazawa 4 , Hiroyasu Ikeno 2 , and Kei Yamada 2

1 Kyoto University, Kyoto, Kyoto, Japan, 2 Kyoto Prefectural University of Medicine, Kyoto, Japan, 3 Siemens AG, Erlangen, Germany, 4 Johns Hopkins University, Maryland, United States

q-space imaging (QSI) can allow us to measure water molecular displacement in micro-meter order and also there have been several attempts to verify the microstructural changes of normal/abnormal human subjects. Nevertheless, because of this long acqusition time, the clinical applications of QSI might have been largely limitted. Therefore, this study aimed to find a feasible combination of q values to be shortening the QSI acquisition for clinical use. For the evaluation, we employed mean displacement (MD) which derived from q-analysis of water molecular displacement distribution.

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