Why should standard eddy-current distortion correction techniques be avoided even for moderately high b-value data?

This work highlights issues with the current practice for correcting eddy-current (EC) distortions on moderately high b-value data and demonstrates their mitigation with a simple alternative. Both techniques are evaluated on real and simulated data, and the importance of EC correction for estimating microstructure is illustrated with the NODDI model. We demonstrate that correcting moderately high b-value data with standard EC correction techniques introduces distortion that compromises the anatomical correspondence between the DWIs and leads to questionable estimates of microstructural features. We show our alterative circumvents these issues and provides good correction.

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