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Abstract #2855

A new fiber bundle pathway identified with diffusion MRI fiber tractography: Fact or fantasy?

Anneriet M Heemskerk 1 , Michel Thiebaut de Schotten 2 , Marco Catani 2 , Silvio Sarubbo 3 , Laurent Petit 4 , Max Viergever 1 , Derek K. Jones 5 , John Evans 5 , Tom Paus 6,7 , and Alexander Leemans 1

1 Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, 2 King's College London, United Kingdom, 3 Santa Chiara Hospital, Italy, 4 GIN-UMR5296, CNRS, CEA, University of Bordeaux, Bordeaux, France, 5 Cardiff University, United Kingdom, 6 Rotman Research institute, Baycrest, Toronto, Canada, 7 Departments of Psychology and Psychiatry, University of Toronto, Toronto, Canada

Diffusion-weighted MRI based fiber tractography (FT) is widely used and its methodology is constantly improving. Despite the many pitfalls and limitations of FT, we present a description of fiber tract pathways in the orbitofrontal / prefrontal cortex, which to the best of our knowledge have not been reported before with FT. A consistent tract configuration across multiple subjects and different data cohorts was observed which boost our confidence that this finding is not based on artifacts.

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