Abstract #2863
Diffusion weighting bias correction for quantitative IVIM metrics in kidney
Dariya Malyarenko 1 , Yuxi Pang 1 , Julien Senegas 2 , Marko Ivancevic 3 , Brian D Ross 1 , and Thomas L Chenevert 1
1
Radiology, University of Michigan, Ann
Arbor, Michigan, United States,
2
Philips
Research Laboratories, Hamburg, Germany,
3
Philips
Healthcare, Best, Netherlands
Nonuniform diffusion weighting bias due to gradient
nonlinearity causes substantial errors in ADC maps for
anatomical regions imaged distant from magnet isocenter.
Our previously-described approach allowed effective
removal of spatial ADC bias for mono-exponential media
of arbitrary anisotropy. Here we evaluate correction
performance for quantitative diffusion parameters of the
IVIM model for renal tissue. Comparable accuracy is
achieved both for corrections based on b-maps and DWI
intensities for slow ADC component in presence of IVIM.
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