Diffusion weighting bias correction for quantitative IVIM metrics in kidney
Dariya Malyarenko 1 , Yuxi Pang 1 , Julien Senegas 2 , Marko Ivancevic 3 , Brian D Ross 1 , and Thomas L Chenevert 1
Radiology, University of Michigan, Ann
Arbor, Michigan, United States,
Research Laboratories, Hamburg, Germany,
Healthcare, Best, Netherlands
Nonuniform diffusion weighting bias due to gradient
nonlinearity causes substantial errors in ADC maps for
anatomical regions imaged distant from magnet isocenter.
Our previously-described approach allowed effective
removal of spatial ADC bias for mono-exponential media
of arbitrary anisotropy. Here we evaluate correction
performance for quantitative diffusion parameters of the
IVIM model for renal tissue. Comparable accuracy is
achieved both for corrections based on b-maps and DWI
intensities for slow ADC component in presence of IVIM.
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