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Abstract #2863

Diffusion weighting bias correction for quantitative IVIM metrics in kidney

Dariya Malyarenko 1 , Yuxi Pang 1 , Julien Senegas 2 , Marko Ivancevic 3 , Brian D Ross 1 , and Thomas L Chenevert 1

1 Radiology, University of Michigan, Ann Arbor, Michigan, United States, 2 Philips Research Laboratories, Hamburg, Germany, 3 Philips Healthcare, Best, Netherlands

Nonuniform diffusion weighting bias due to gradient nonlinearity causes substantial errors in ADC maps for anatomical regions imaged distant from magnet isocenter. Our previously-described approach allowed effective removal of spatial ADC bias for mono-exponential media of arbitrary anisotropy. Here we evaluate correction performance for quantitative diffusion parameters of the IVIM model for renal tissue. Comparable accuracy is achieved both for corrections based on b-maps and DWI intensities for slow ADC component in presence of IVIM.

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