Abstract #2864
Use of a Multi-Exponential Attenuation Model for Sequential Registration of Diffusion Weighted Imaging in the Abdomen and Pelvis
Matthew R Orton 1 , Neil Peter Jerome 1 , Evangelia Kaza 1 , David J Collins 1 , Dow-Mu Koh 2 , Bernd Kuehn 3 , and Martin O Leach 1
1
Radiotherapy and Imaging Department,
Institute of Cancer Research, Sutton, Surrey, United
Kingdom,
2
Department
of Radiology, Royal Marsden Hospital, Sutton, Surrey,
United Kingdom,
3
Siemens
Medical Solutions, Erlangen, Germany
Imaging in the abdomen and thorax is more challenging
than other regions due to various forms of tissue
motion. For diffusion weighted imaging, registration
techniques need to be robust to the wide range of image
brightness and contrast over the b-values typically
used. This abstract presents an image registration
algorithm for diffusion weighted images that uses a
multi-exponential model of signal attenuation to
sequentially synthesize target images with matching
brightness and contrast on which to register the source
images. This technique is highly effective for removing
in-plane motion with coronally acquired images.
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