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Abstract #2879

In vivo diffusion tensor imaging and tractography of human brain at submillimeter isotropic resolution on a clinical MRI scanner

Mark Sundman 1 , Hing-Chiu Chang 1 , Laurent Petit 2 , Shayan Guhaniyogi 1 , Christopher Petty 1 , Allen Song 1 , and Nan-kuei Chen 1

1 Brain Imaging and Analysis Center, Duke University Medical Center, Durham, North Carolina, United States, 2 Groupe d'Imagerie Neurofonctionnelle (GIN) - UMR5296, CNRS, CEA, Universit de Bordeaux, Bordeaux, France

This research introduces a novel mothed for high-resolution diffusion tensor imaging (DTI) that is capable of achieving submillimeter isotropic resolution (0.85 x 0.85 x 0.85 mm3) in vivo for the human brain using a normal 3T clinical scanner. This high-resolution DTI enables both researchers and physicians to more accurately identify white matter structures and fiber tracts in vivo. To demonstrate its utility and potential, we identified structures at this submillimeter isotropic resolution that are indiscernible at conventional resolutions.

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