Abstract #2923
Clinical application of gamma distribution model for spinal lesions: Initial clinical results
Miyuki Takasu 1 , Koichi Oshio 2 , Yuji Akiyama 1 , Ryuji Akita 1 , Kazushi Yokomachi 1 , Yoko Kaichi 1 , Shuji Date 1 , and Kazuo Awai 1
1
Diagnostic Radiology, Hiroshima University
Hospital, Hiroshima, Hiroshima, Japan,
2
Department
of Diagnostic Radiology, Keio University, Tokyo, Japan
Non-Gaussian diffusion methods permitting the analysis
of the diffusion-weighted signal over a larger range of
b-values have gained an increasing importance in tissue
characterization. Our purpose was to investigate the
applicability and the performance of gamma distribution
model in differentiating vertebral lesions in human
subjects. For each of normal spinal bone marrow and
lesions, , , the area fraction of D < 1.0mm2/s
(frac<1), the area fraction of D > 3.0 mm2/s (frac>3),
PG (D) and K was measured. , frac <1, PG (D), and K
proved to be useful for differentiation of malignant
lesions from benign lesions.
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