Abstract #2932
Towards High Spatial Resolution Diffusion-Sensitized MR Imaging of the Eye and Orbit at 3.0 T and 7.0 T: Quantitative Assessment of the Anatomic Fidelity of EPI and RARE Variants
Katharina Paul 1 , Andreas Graessl 1 , Jan Rieger 1,2 , Darius Lysiak 1,2 , Till Huelnhagen 1 , Lukas Winter 1 , Robin Heidemann 3 , Tobias Lindner 4 , Stefan Hadlich 5 , Paul-Christian Krueger 5 , Soenke Langner 5 , Oliver Stachs 4,6 , and Thoralf Niendorf 1,7
1
Max-Delbrueck Centre for Molecular Medicine,
Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin,
Berlin, Germany,
2
MRI.TOOLS
GmbH, Berlin, Germany,
3
Siemens
Healthcare Sector, Erlangen, Germany,
4
University
Medicine Rostock, Pre-clinical Imaging Research Group,
Rostock, Germany,
5
University
of Greifswald, Institute for Diagnotic Radiology and
Neuroradiology, Greifswald, Germany,
6
University
Medicine Rostock, Department of Ophthalmology, Rostock,
Germany,
7
Experimental
and Clinical Research Center, a joint cooperation
between the Charit Medical Faculty and the
Max-Delbrueck-Center, Berlin, Germany
Diffusion-weighted imaging (DWI) of the orbit is an
emerging MRI application to provide guidance during
diagnostic assessment and treatment of ophthalmological
diseases. The standard approach for DWI is EPI. However,
EPI is prone to severe geometric distortions, especially
at high and ultrahigh magnetic fields. Realizing these
constraints and the potential of ocular DWI, this work
uses diffusion sensitized multi-shot RARE for ophthalmic
MRI. A comparison in terms of geometric distortions of
ms-RARE with two EPI variants is performed for brain and
ocular imaging at 3.0 T and at 7.0 T.
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