Abstract #2940
High angularly resolved diffusion imaging with short scan time and low distortion
Tzu-Cheng Chao 1,2 , Jr-Yuan George Chiou 3 , Stephan E. Maier 3 , and Bruno Madore 3
1
Department of Computer Science and
Information Engineering, National Cheng-Kung University,
Tainan, Taiwan,
2
Institute
of Medical Informatics, National Cheng-Kung University,
Tainan, Taiwan,
3
Department
of Radiology, Brigham and Women's Hospital, Harvard
Medical School, Boston, M.A., United States
High angular resolution diffusion imaging is a useful
tool in exploring cerebral microstructure, but long scan
times and geometric distortions have impeded its
translation to clinical practice. In the present work, a
strategy integrating advantages from accelerated
multishot diffusion imaging, multiplexed sensitivity
encoding and compressed sensing is proposed to provide
reductions in scan time and in geometric distortions.
Four-fold improvements in distortion level and as much
as three-fold reductions in scan time were achieved for
HARDI acquisitions.
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