Abstract #2943
An optimized protocol for neurite orientation dispersion and density imaging (NODDI) in preclinical studies
Andreia C. Silva 1 , Eleni Demetriou 1 , Magdalena Sokolska 1 , Mohamed Tachrount 1 , Niall Colgan 2 , Bernard Siow 2 , Mark F. Lythgoe 2 , Xavier Golay 1 , and Hui Zhang 3
1
Department of Brain Repair and
Rehabilitation, UCL Institute of Neurology, London,
London, United Kingdom,
2
Centre
for Advanced Biomedical Imaging, University College
London, London, United Kingdom,
3
Department
of Computer Science and Centre for Medical Image
Computing, University College London, London, London,
United Kingdom
Neurite Orientation Dispersion and Density Imaging (NODDI)
is a recent model-based diffusion MRI technique that has
gained rapid uptake in the clinical setting owing to the
availability of an economical protocol. This work aims
to empirically determine a similar protocol for the
preclinical setting that provides the best trade-off
between acquisition time and accuracy of parameter
estimation. By assessing a broad range of the subset
protocols extracted from a rich dataset with many
b-values and repetitions, we find that NODDI parameters
can be accurately estimated with a protocol that is less
than an hour.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
