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Abstract #2950

Impact of noise bias with parallel imaging for axon diameter estimation with q-space MRI

T. Duval 1 , T. Witzel 2 , B. Keil 2 , L. L. Wald 2 , V. Smith 2 , E. Klawiter 2 , and J. Cohen-Adad 1,3

1 Institute of Biomedical Engineering, Polytechnique Montral, Montral, Qubec, Canada, 2 A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States, 3 Functional Neuroimaging Unit, CRIUGM, Universit de Montral, Montral, Qubec, Canada

Parallel imaging is commonly used in q-space diffusion MRI for reducing susceptibility distortions and scan time. However its impact on diffusion measurements is still poorly studied and might introduce some bias at high b-value due to non-spatially uniform noise level. In this work we compared AxCaliber results in the human spinal cord using GRAPPA and a reduced field of view technique.

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