Meeting Banner
Abstract #2953

A novel method to estimate labeling efficiency for pseudo-continuous arterial spin labeling imaging

Zhensen Chen 1,2 , Xingxing Zhang 2 , Andrew G. Webb 2 , Xihai Zhao 1 , and Matthias J.P. van Osch 2

1 Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2 C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Zuid-holland, Netherlands

A novel method based on multi-phase pseudo-continuous ASL (pCASL) imaging distal to the labeling plane was proposed to estimate labeling efficiency. The acquired in vivo ASL signals were consistent with the expected curves from simulations of pCASL imaging using laminar flow model. The labeling efficiencies calculated from in vivo data were in line with theoretical simulation in spite of some measurement errors that might be due to cardiac pulsation and partial volume effect. The method is fast, promising and requires more investigation for improvement of robustness and quantification.

This abstract and the presentation materials are available to members only; a login is required.

Join Here