Cardiac-triggered pCASL: A cost-effective scheme to enhance the SNR of ASL

The current recommended protocol for ASL is to use pseudocontinuous labeling with 3D acquisition after background suppression. With the recommended long labeling time (1.8s) and post-labeling delay time (1.8s), it is generally thought that the effect of cardiac pulsation should be minimal. However, we often observe the existence of large fluctuations in the difference image (control-label) intensity from one volume to another. Here, we show that the global signal fluctuations is largely attributed to cardiac phase differences from one volume to another, and that cardiac-gated pCASL can increase the SNR by 79% at a modest cost of scan time.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.