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Abstract #2971

Multi-voxel pattern analysis delineates selective ASL-collateral supply in patients with intracranial stenosis

Andrea Federspiel 1 , Simon Schwab 1 , Mirjam R. Heldner 2 , Urs Fischer 2 , Jan Gralla 3 , and Roland Wiest 3

1 Psychiatric Neurophysiology, University Hospital of Psychiatry, Bern, Bern, Switzerland, 2 Inselspital, University of Bern, Department of Neurology and Stroke Center, Bern, Bern, Switzerland, 3 Inselspital, University of Bern, Institute of Diagnostic and Interventional Neuroradiology, Bern, Bern, Switzerland

In the present study perfusion territories are assessed by vessel-encoded (VE) pseudo-continuous arterial spin labeling (p-CASL) in a cohort of 45 patients with intracranial stenosis. The features of a classification analysis performed with the framework of searchlight multi-voxel pattern analysis (MVPA) were investigated. The hypothesis was tested how accurate the classification (above chance level of 0.5) can be performed in these patients. Classification was high in left-, right and posterior perfusion territories with an overlap on the stenotic side. These findings suggest that the present classification method is sensitive to collateral flow.

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