Abstract #2971
Multi-voxel pattern analysis delineates selective ASL-collateral supply in patients with intracranial stenosis
Andrea Federspiel 1 , Simon Schwab 1 , Mirjam R. Heldner 2 , Urs Fischer 2 , Jan Gralla 3 , and Roland Wiest 3
1
Psychiatric Neurophysiology, University
Hospital of Psychiatry, Bern, Bern, Switzerland,
2
Inselspital,
University of Bern, Department of Neurology and Stroke
Center, Bern, Bern, Switzerland,
3
Inselspital,
University of Bern, Institute of Diagnostic and
Interventional Neuroradiology, Bern, Bern, Switzerland
In the present study perfusion territories are assessed
by vessel-encoded (VE) pseudo-continuous arterial spin
labeling (p-CASL) in a cohort of 45 patients with
intracranial stenosis. The features of a classification
analysis performed with the framework of searchlight
multi-voxel pattern analysis (MVPA) were investigated.
The hypothesis was tested how accurate the
classification (above chance level of 0.5) can be
performed in these patients. Classification was high in
left-, right and posterior perfusion territories with an
overlap on the stenotic side. These findings suggest
that the present classification method is sensitive to
collateral flow.
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