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Abstract #2981

Choices in processing steps for diffusion MRI analyses: Does it really matter?

Szabolcs David 1 , Chantal M. W. Tax 1 , Max A. Viergever 1 , Anneriet Heemskerk 1 , and Alexander Leemans 1

1 Image Sciences Institute, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands

Different implementations of processing steps such as correction for subject motion and artifacts (e.g., eddy current induced distortions and susceptibility related deformations), spatial normalization, and estimation approach used during diffusion MRI analysis may provide different results, but whether such potential differences are significant for a typical tract analysis remains unknown. In this work, we investigated the effect of tensor estimation approach and interpolation strategy on diffusion measures for a tractography based study.

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