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Abstract #2993

Ventral Intermediate Nucleus (VIM) Localization with Probablistic Diffusion Tractography

Chia-Chu Chou 1,2 , Prashant Raghavan 1 , Dheeraj Gandhi 1 , Rao P Gullapalli 1 , and Jiachen Zhuo 1

1 Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States, 2 Electrical and Computer Engineering, University of Maryland, College Park, Maryland, United States

Thalamotomy targeting VIM has been proved to be an efficient treatment against tremor. However, the localization process for VIM is challenging. Atlas-based coordinate methods commonly adopted does not account for patient specific anatomy variation. In this study, we showed preliminary evidence that we can use probabilistic tractography to identify cortical region that has unique connectivity with VIM in the thalamus. Our tracked VIM region from cortical connectivity showed good correspondence (67% volume overlap) with the altas-based VIM mask. We expect this new method can further facilitate the process of future thalatomy surgical planning.

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