Alterations in white matter tracts in alcohol dependence: A Tract-Based Spatial Statistics (TBSS) based DTI study

The aim of present study was to investigate micro-structural disruption of white matter tracts in alcohol dependant subjects by using Tract-Based Spatial Statistics (TBSS) of DTI measures. DTI was performed on twenty-nine control subjects and twenty-eight alcoholic patients. Our result showed decreased fractional anisotropy in the anterior thalamic radiation, inferior fronto-occipital fasciculus, superior and inferior longitudinal fasciculus, forceps minor,corticospinal, cingulum, uncinate fasciculus in alcohol dependant subjects as compared to controls. These findings suggest that the microstructural changes in these white matter tracts may contribute to underlying dysfunction in cognitive and behaviour as observed in them.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.