Abstract #3014
Diffusion Tensor Imaging of the human aortic wall: an ex-vivo study
Nicola Martini 1 , Simona Celi 1,2 , Daniele Della Latta 1 , Daniele De Marchi 1 , Giuseppe Valvano 1,3 , Angelo Monteleone 1 , Vincenzo Positano 4 , Maria Filomena Santarelli 4,5 , Sergio Berti 1 , Marco Solinas 1 , Luigi Landini 1,3 , and Dante Chiappino 1
1
Fondazione G.Monasterio CNR-Regione Toscana,
Massa, MS, Italy,
2
Scuola
Superiore Sant'Anna, Pisa, PI, Italy,
3
Department
of Information Engineering, University of Pisa, Pisa,
PI, Italy,
4
Fondazione
G.Monasterio CNR-Regione Toscana, Pisa, PI, Italy,
5
Institute
of Clinical Physiology, CNR, Pisa, PI, Italy
Diffusion tensor imaging (DTI) provides noninvasive
information on tissue microstructure. However, the
spatial resolution of DTI scans is typically limited by
low signal-to-noise ratio and artifact issues that
prevent its potential application to small structures,
such as vessel walls. In this study we explore the use
of a multi-shot EPI sequence for high resolution DTI
scans of ex-vivo samples of the human aorta. Different
scan protocols are compared to test the influence of
scan parameters (resolution, b-value, number of
diffusion gradient directions, number of signal
averages) on DTI quantitative parameters.
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