Meeting Banner
Abstract #3022

Intravoxel incoherent motion MR imaging: diffusion and perfusion characteristics in early assessment of chemotherapy response in nasopharyngeal carcinoma

Zhuangzhen He 1 , Yunbin Chen 1 , Youping Xiao 1 , Minfeng Li 1 , Weibo Chen 2 , and He Wang 3

1 Fujian Province Cancer Hospital, Fuzhou, Fujian, China, 2 Philips Healthcare, Shanghai, China, 3 Philips Research China, Shanghai, China

IVIM MR imaging was conducted on untreated NPC cases during two cycle of induction chemotherapy. The diffusion and perfusion characteristics D, D*and f were derived and the alterations of maximum tumor diameter were measured. We found D ascended continually with the earliest significant rise at day 3 while D* fluctuated momentarily at the first cycle. Patients was considered responders and non-responders referring to the RECIST criteria after chemotherapy. D and f of responders showed a higher tendency than non-responders. IVIM is feasible in detecting early diffusion and perfusion response to chemotherapy in NPC and potentially helpful with prognosis determination.

This abstract and the presentation materials are available to members only; a login is required.

Join Here