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Abstract #3024

Monitoring The Progressive Changes In Kidney Diffusion And Perfusion In Contrast-induced Nephropathy Using IVIM MRI

Shuixing Zhang 1 , Wenbo Chen 1 , Long Liang 1 , Kannie W.Y. Chan 2 , Yuguo Li 2 , Bin Zhang 1 , Guanshu Liu 2 , and Changhong Liang 1

1 Radiology, Guangdong Academy of Medical Sciences/Guangdong General Hospital, Guangzhou, Guangdong, China, 2 Russell H. Morgan Department of Radiology and Radiological Sciences, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD, United States

Contrast-induced nephropathy(CIN) is a common iatrogenic kidney disease that can cause long-term morbidity and mortality in elderly patients and patients with pre-existing kidney insufficiency or diabetes. The aim of our study is to examine the feasibility of using Intravoxel Incoherent Motion (IVIM) MRI to simultaneously measure the pathological changes in kidney diffusion and perfusion in the course of (CIN). Our results showed that the kidney perfusion and diffusion as measured by IVIM are well-correlated with those measured using conventional methods, indicating IVIM MRI can be used as an effective tool for the diagnosis and staging of CIN.

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