Monitoring The Progressive Changes In Kidney Diffusion And Perfusion In Contrast-induced Nephropathy Using IVIM MRI
Shuixing Zhang 1 , Wenbo Chen 1 , Long Liang 1 , Kannie W.Y. Chan 2 , Yuguo Li 2 , Bin Zhang 1 , Guanshu Liu 2 , and Changhong Liang 1
Radiology, Guangdong Academy of Medical
Sciences/Guangdong General Hospital, Guangzhou,
H. Morgan Department of Radiology and Radiological
Sciences, Division of MR Research, The Johns Hopkins
University School of Medicine, Baltimore, MD, United
Contrast-induced nephropathy(CIN) is a common iatrogenic
kidney disease that can cause long-term morbidity and
mortality in elderly patients and patients with
pre-existing kidney insufficiency or diabetes. The aim
of our study is to examine the feasibility of using
Intravoxel Incoherent Motion (IVIM) MRI to
simultaneously measure the pathological changes in
kidney diffusion and perfusion in the course of (CIN).
Our results showed that the kidney perfusion and
diffusion as measured by IVIM are well-correlated with
those measured using conventional methods, indicating
IVIM MRI can be used as an effective tool for the
diagnosis and staging of CIN.
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