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Abstract #3027

Using oscillating gradient spin-echo sequences to infer micron-sized bead and pore radii

Sheryl L Herrera 1 , Morgan E Mercredi 1 , Trevor J Vincent 2,3 , Richard Buist 4 , and Melanie Martin 2,5

1 Physics & Astronomy, University of Mantioba, Winnipeg, Manitoba, Canada, 2 Physics, University of Winnipeg, Winnipeg, Manitoba, Canada, 3 Physics, University of Toronto, Toronto, Ontario, Canada, 4 Radiology, University of Mantioba, Winnipeg, Manitoba, Canada, 5 Physics & Astronomy, Radiology, University of Mantioba, Winnipeg, Manitoba, Canada

There is an increasing drive to use diffusion spectroscopy to infer the sizes of structures in samples yet pulsed gradient spin echo limits the obtainable sizes. This work provides experimental evidence for using oscillating gradient spin echo sequences to infer the sizes of small structures. Structures of radius 0.6 0.5 m were inferred using this method which is 2-10 times smaller than structures measured with AxCaliber and more accurate than previous measurements. This work lays the foundation for inferring the size of submicron structures, such as axon diameters in samples using MRI.

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