Abstract #3028
How to get more out of a clinically feasible 64 Gradient dMRI Acquisition: Multi-Shell versus Single-Shell
Rutger Fick 1 , Mauro Zucchelli 2 , Gabriel Girard 1,3 , Gloria Menegaz 2 , Maxime Descoteaux 3 , and Rachid Deriche 1
1
Team Athena - INRIA, Sophia Antipolis, Alpes
Maritimes, France,
2
University
of Verona, Verona, Italy,
3
Sherbrooke
Connectivity Imaging Lab (SCIL), Computer Science
Department, Quebec, Canada
In clinical applications for diffusion MRI the maximum
number of samples is often limited by practical
constraints. Given a clinically feasible 64 direction
acquisition, we compare the single-shell approach, which
samples at a single b-value, with a multi-shell
approach, which spreads the same number of samples over
multiple b-values. We show that using the continuous
analytical bases 3D-SHORE and MAP-MRI on multi-shell
data we can have a better estimation of both the white
matter directionality using the ODF, and microstructural
features such as the axon radius, without increasing the
number of samples.
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