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Abstract #3050

High-resolution Whole-brain DCE MRI of Brain Tumor using Constrained Reconstruction: Prospective Clinical Evaluation

Yi Guo 1 , R. Marc Lebel 2 , Yinghua Zhu 1 , Mark S. Shiroishi 3 , Meng Law 3 , and Krishna S. Nayak 1

1 Department of Electrical Engineering, University of Southern California, Los Angeles, CA, United States, 2 GE Healthcare, Calgary, Alberta, Canada, 3 Department of Radiology, University of Southern California, Los Angeles, CA, United States

Here we present the first prospective clinical evaluation of whole-brain DCE MRI, based on sparse sampling and constrained reconstruction, in brain tumor patients. Results were compared with the conventional clinical approach in the same patients during the same examination. While performed in the same amount of time, experimental DCE MRI is able to realize near-isotropic resolution and whole-brain coverage without compromise of image quality in the ROI as the conventional approach.

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