Abstract #3058
Retrospective Resolution Adaption for DCE MRI Using 3D Golden Angle Radial Acquisition
Ina Nora Kompan 1,2 , Benjamin Richard Knowles 3 , Cristoffer Cordes 1 , and Matthias Guenther 1,2
1
Fraunhofer MEVIS, Bremen, Bremen, Germany,
2
mediri
GmbH, Heidelberg, Baden-Wrttemberg, Germany,
3
Universittsklinikum
Freiburg, Freiburg, Baden-Wrttemberg, Germany
In dynamic contrast-enhanced MRI, pharmacokinetic
modeling is used to quantify tissue physiology. The
maximal allowed spatial resolution to still guarantee
accurate model fitting depends on the shape of the
signal time curve S(t), which is not a priori known. In
this work, a 3D golden angle (GA) radial sequence is
used to retrospectively adapt spatial resolutions to S(t)
throughout the time interval to achieve the maximal
feasible spatial resolutions. Using a perfusion phantom,
it is shown that, compared to a high temporal and low
spatial resolution sequence, the spatial resolution of
parameter maps is improved at the same fitting accuracy.
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