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Abstract #3193

RF pulse designs for MPRAGE at 9.4T

Desmond Ho Yan Tse 1,2 , Daniel Brenner 3 , Johannes G Ramaekers 1 , Joachim E Wildberger 2 , and Benedikt A Poser 1

1 Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 2 Department of Radiology, Maastricht University Medical Centre, Maastricht, Netherlands, 3 German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany

T1-weighted imaging with MPRAGE at 9.4T was improved by using TR-FOCI for inversion and kt-points pulses for excitation. Due to the higher inversion effectiveness of TR-FOCI over hyperbolic secant at low B1+, uniform inversion across the whole brain was achieved. Meanwhile, the excitation inhomogeneity was reduced across the whole brain by replacing the rectangular excitation pulse in CP mode with a MLS optimised full pTx kt-points composite pulse. The improvements from these two modifications have led to reductions in intensity variation due to transmit and contrast loss due to in sufficient B1+ for inversion in the resulting T1-weighted image.

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