7T MRSI using Semi-Adiabatic Spectral-spatial Spectroscopic Imaging (SASSI) for improved B1-insensitivity in refocusing and reduced chemical shift artifact

High magnetic fields permit us to leverage increased signal-to-noise ratio and spectral separation between metabolite peaks for more sensitive metabolite detection and quantification as well as higher resolution spectral grids. With high field strengths come challenges such as increased RF power deposition, B1-inhomogeneity, and increased chemical shift artifacts. We used the adiabatic Shinnar Le-Roux algorithm to create a Semi-Adiabatic Spectral-spatial Spectroscopic Imaging (SASSI) sequence to capture the main metabolites at 7T. The sequence was designed to generate spectroscopic grids with improved B1-immunity and reduced chemical shift artifact while having lower SAR than existing adiabatic implementations.

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